Divalent Cation Interactions with Light-Dependent K Channels

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Divalent Cation Interactions with Light-Dependent K Channels

The light-dependent K conductance of hyperpolarizing Pecten photoreceptors exhibits a pronounced outward rectification that is eliminated by removal of extracellular divalent cations. The voltage-dependent block by Ca(2+) and Mg(2+) that underlies such nonlinearity was investigated. Both divalents reduce the photocurrent amplitude, the potency being significantly higher for Ca(2+) than Mg(2+) (...

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1999

ISSN: 0022-1295,1540-7748

DOI: 10.1085/jgp.114.5.653